Baked Parmesan Artichoke Chicken

Baked Parmesan Artichoke Chicken is a yummy weeknight meal with chicken, parmesan cheese, and artichoke hearts in a creamy sauce.

There’s nothing better than an easy Chicken Dinner Recipe to try out when you’re tired of your old favorites. Quick weeknight meals like Crispy Butter Chicken, Baked Spinach Artichoke Chicken, and Brown Sugar Garlic Chicken are some of the most delicious chicken dinners you’ll ever try, and ready in about a half hour.

If you want an easy weeknight dinner that has a short cook time and is both hearty and delicious, then this is the recipe for you. Baked Parmesan Artichoke Chicken is a great comfort food dish that you can make ahead of time and reheat when you need something quick and delicious in a pinch. In fact, it’s so easy that it may end up being one of your new favorite dinner recipes.

You simply mix mayonnaise with Parmesan cheese, minced garlic, salt and pepper and top your boneless skinless chicken breasts, then bake for 30 minutes and you’re done! As it bakes, the chicken juices meld with the mayonnaise mixture to create a rich, savory artichoke sauce. The result is a flavorful chicken dish with enough savory sauce to serve atop rice, pasta, or with fresh Dinner Rolls for dipping.

The great thing about this yummy chicken dinner is that it’s packed full of flavor, but it’s also easy to make. It’s a simple recipe that you can prepare in minutes, so you don’t have to spend the whole afternoon in the kitchen wrestling with complicated ingredients.  As far as comfort food goes, this ticks a lot of boxes: it’s savory, it’s hearty and it’s made from ingredients that you may already have lying around.

Serve Baked Parmesan Artichoke Chicken with classic side dishes like Roasted Garlic Butter Mushrooms and Easy Mashed Potatoes, and finish the meal with Tiramisu for an easy Italian-American dinner at home.

How to Make Baked Parmesan Artichoke Chicken

• Preheat oven to 375 degrees.
• In a medium bowl, mix together the artichoke hearts, Parmesan cheese, mayonnaise, garlic, salt, and pepper.
• Place chicken in a greased baking dish, and cover evenly with artichoke mixture.
• Bake, uncovered, for 30 minutes in the preheated oven, or until chicken is no longer pink in the center and juices run clear.

Easy Chicken Parmesan

Crispy Baked Lemon Parmesan Chicken

Creamy Garlic Parmesan Roasted Chicken

Parmesan Crusted Chicken

Frequently Asked Questions

Key Ingredients in Baked Parmesan Artichoke Chicken

• Chicken: Boneless skinless chicken breasts will cook evenly and quickly. Cut each breast in half lengthwise to create 4 thinner cutlets. This allows each piece to have more surface area for the artichoke topping to be spread on top.
• Artichoke Hearts: Canned artichoke hearts are typically packed in a briny liquid. Drain off the liquid and pat them dry with paper towels to prevent them from making your sauce runny.
• Mayonnaise: The mayonnaise is a tangy base for your Parmesan artichoke topping. Use regular full fat mayonnaise for the best flavor and creamiest result. 

Slow Cooker Baked Parmesan Artichoke Chicken

• Prepare chicken breasts by cutting in half lengthwise and placing on the bottom of a Crock Pot that’s been sprayed lightly with oil.
• Mix the artichoke hearts with Parmesan cheese, mayonnaise, garlic, salt and pepper, and spread mixture on top of the chicken.
• Cook on high for 3-4 hours until the chicken is cooked through.

Can Baked Parmesan Artichoke Chicken Be Made Ahead?

If you want to make your dinnertime even easier, for the instructions for Baked Parmesan Artichoke Chicken and stop before the baking step. Cover tightly with plastic wrap and place in the refrigerator up to 24 hours in advance. When you are ready for dinner, simply preheat your oven, remove the plastic wrap and bake at 375 for 30 minutes. Take the baking dish out of the refrigerator while the oven is pre-heating so that it is not as cold when it goes into the oven.

You can also use Baked Parmesan Artichoke Chicken for easy meal prep. After baking, portion the 4 chicken pieces with white rice, pasta noodles, or mashed potatoes. If you are on a Keto or low-carb diet, pair it with cauliflower rice, zoodles, or a fresh green salad. Then just reheat and enjoy for an easy lunch or dinner.

What to do with Leftover Baked Parmesan Artichoke Chicken

Leftover Baked Parmesan Artichoke Chicken can be reused in many delicious ways. Chop the chicken into pieces and toss it with cooked pasta for a cold Parmesan Artichoke Chicken Pasta Salad. Add a little Italian dressing or mayonnaise if it is too dry. You can also reheat the artichoke chicken and place it on a crusty toasted French roll along with melted provolone cheese for a delicious hot chicken artichoke sandwich. Or shred the chicken and mix it into the Parmesan artichoke sauce, add some shredded mozzarella cheese on top and reheat it all together. Then eat it with crackers or tortilla chips for a yummy dip.

Variations on Baked Parmesan Artichoke Chicken

• Protein: If you prefer dark meat, use boneless skinless chicken thighs instead of breasts for this baked chicken dish. This recipe would also be delicious with boneless pork cutlets or turkey breast cutlets.
• Veggies: To add more flavor and nutrition to your chicken dinner, mix 1 cup frozen spinach, rinsed and drained well, into the mayonnaise mixture. Increase the mayonnaise to 1 cup.
• Spices: You can add a dash of red pepper flakes, paprika, or any other spices you’d like to play with the flavor without having to switch up any of the other ingredients. If you don’t have any garlic cloves, you can use garlic powder instead of running to the store.
• Herbs: Add your favorite fresh or dried Italian herbs like oregano, parsley, basil, marjoram, or thyme to the mayonnaise mixture before topping the chicken.
• Dairy: Replace half of the mayonnaise with sour cream, greek yogurt, or softened cream cheese to add a creamy finish and extra flavor to the Parmesan artichoke sauce.
• Cheese: Add more cheesy flavor by sprinkling shredded mozzarella cheese, provolone, Pecorino Romano or Asiago on the artichoke chicken dish in the last 10 minutes of baking.
• Lemon: Add 2 tablespoons of fresh lemon juice and 1 tablespoon lemon zest into the mayonnaise mixture to add a zesty lemon flavor to Baked Parmesan Artichoke Chicken.
• Breadcrumb Topping: Melt 2 tablespoons butter and combine with 1 cup of breadcrumbs, panko, or crushed Ritz crackers. Optionally add ½ cup parmesan cheese and ½ teaspoon salt. Sprinkle on top of artichoke mixture before baking.

What to Serve with Baked Parmesan Artichoke Chicken

Garlic Bread

Olive Garden Italian Salad Dressing (Copycat)

Tomato Mozzarella Salad

Rainbow Roasted Vegetables

How to Store Baked Parmesan Artichoke Chicken

• Serve: You should never leave your Baked Parmesan Artichoke Chicken out at room temperature for longer than about 2 hours after cooking for health reasons.
• Store: Let the chicken completely cool down to room temperature, then wrap it in plastic wrap or put it in an airtight container and it will last for up to 3 days before it’s time to make a new batch.
• Freeze: Wrap up the Baked Parmesan Artichoke Chicken in an airtight container and it will last for up to 3 months in the freezer.